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CRISPR screen of venetoclax response-associated genes identifies transcription factor ZNF740 as a key functional regulator

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Abstract BCL-2 inhibitors such as venetoclax offer therapeutic promise in acute myeloid leukemia (AML) and other cancers. but drug resistance poses a significant challenge. It is crucial to understand the mechanisms that regulate venetoclax response. While correlative studies have identified numerous genes linked to venetoclax sensitivity. https://lecoureures.shop/product-category/collections/
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