The germinal center (GC) reaction is a key feature of adaptive humoral immunity. GCs represent the site where mature B cells refine their B-cell receptor (BCR) and are selected based on the newly acquired affinity for the antigen. In the GC. B cells undergo multiple cycles of proliferation. https://www.markbroyard.com/hot-sale-us-topo-7-5-minute-map-for-sunken-lake-mi-supply-limited-grab/